There are some bad things that happen to good people at least once in a lifetime. Getting fired from a job. Getting a speeding ticket. Stuff you try to avoid. This past Sunday I was in Manhattan for the day with my partner Julio. We go in often enough that it's fairly routine. I carry my meds with me for the day. I start to fade around 3 or 4pm, take the train home at that time, Julio comes back later in the evening. No problem. But this time J. said stay till 8pm & then i'll come back with you. I just was not thinking. I took my last dose at 6:30pm. I had no extra stash at all. Nada. Zip. Zero. I keep extra doses in my car, but that was parked back in Jersey. I screwed up. I was panic stricken. We missed the 7pm train out of Penn Station, the next one was at 8pm. What a nightmare. Of course the train was full of loud drunks, screaming babies, the whole nine yards. I was not a pretty sight. So I learned the hard way NEVER to go anywhere, anytime, anyplace without lots of extra carbidopa/levodopa. Each dose only lasts 2 1/2 hours. Now I know why the "off-state" is often mistaken for being drunk when strangers see you in public. I guess it happens to any person with PD at least once. But you'd think that after living 9 years with PD, I'd know better !
My bladder issues with PD are a real drag ! Some people do not know that your brain "controls" your bladder. Cells in the portion of the brain associated with urine control produce a chemical called Dopamine . Its release helps to keep the bladder in the off condition (bladder is relaxed while filling with urine), and prevents the bladder from contracting - when the bladder becomes full, the brain is alerted and then signals the bladder to contract (turn on ) to release urine. In PD, these cells are lost or reduced in number resulting in bladder on and off problems. My biggest issues so far have been overactive bladder and not being able to urinate at all. Overactive bladder for me means sudden urgency but not sure how full my bladder is until I get to the john (feels very full but may not be.) Not being able to urinate at all is serious - I have plenty of disposable intermittent catheters and lube whenever that suddenly happens...Loads of fun ...
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